Clinical analysis of yuziwan in the treatment of 30 sterile men with abnormal protamine.
- Author:
Xu-chu WANG
1
;
Hai-song LI
;
Tian-ming PAN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Drugs, Chinese Herbal; therapeutic use; Histones; metabolism; Humans; Infertility, Male; drug therapy; metabolism; Male; Phytotherapy; Protamines; metabolism
- From: National Journal of Andrology 2006;12(11):1044-1046
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the clinical application and effects of Yuziwan in the treatment of male sterility patient with abnormal protamine.
METHODSThe changes of protamine, semen and sex hormones of 30 male sterility patients treated by Yuziwan were observed before and after the treatment.
RESULTSAfter a 3-month course of treatment, 9 cases were cured, 15 obviously improved and 6 failed to respond. The ratio of histone to protamine was decreased from (1.34 +/- 0.52) before the treatment to (0.72 +/- 0.32) after it, with significant difference (P < 0.01), the semen quality obviously improved (P < 0.05), and the LH and T levels markedly raised (P < 0.01). Yuziwan evidently improved the abnormal protamine, sperm quality and endocrine function of the sterility patients.
CONCLUSIONYuziwan has good curative effect on male sterility.