Adhesion to buccal epithelial cells of Candida albicans isolates from oral lichen planus.

Author: Xin ZENG ¹ ; Qian-ming CHEN ; Min-hai NIE ; Bing-qi LI
Author Information

1. Dept of Oral Medicine, West China College of Stomatology, Sichuan University, Chengdu.
Publication Type:Journal Article
MeSH: Candida albicans; Cell Adhesion; Epithelial Cells; Humans; Lichen Planus, Oral
From: West China Journal of Stomatology 2005;23(6):537-538
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo investigate the adhesion to buccal epithelial cells of Candida albicans isolates from erosive oral lichen planus (OLP) and nonerosive OLP, and its role in the development of OLP.
METHODSA total of 112 isolates, comprising healthy control (26), erosive OLP (62) and nonerosive OLP (24), were screened for the adhesion by using buccal epithelial cell (BEC) assay.
RESULTSThe adhesion to buccal epithelial cells of the isolates from erosive OLP group was stronger than that of those from healthy control.
CONCLUSIONCandida albicans, some isolates with a special virulence attribute may contribute to the occurrence and progression of erosive OLP.