Immunohistochemical study of heme oxygenase-1 expressed in human normal dental pulp cell and tissue.
- Author:
Fan YANG
1
;
Zhen-yu HU
;
Hao FANG
;
Zhi-qiang CAO
Author Information
- Publication Type:Journal Article
- MeSH: Cell Differentiation; Dental Pulp; Dentin; Fibroblasts; Heme Oxygenase-1; Humans; Odontoblasts
- From: West China Journal of Stomatology 2006;24(2):104-109
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the expression of heme oxygenase-1 (HO-1) in dental pulp tissue and to find out the relationship of distribution and function of HO-1.
METHODS30 pulp tissues were obtained from clinically extracted human healthy premolars and third molars. The expression of HO-1 in dental pulp was detected by means of SABC immunohistochemical technology.
RESULTSHO-1 immunoreactivity was observed in vascular endothelial cells, odontoblasts and some fibroblasts cells.
CONCLUSIONThe distribution of HO-1 in normal human dental pulp suggests that HO-1 may play an important role in pulp flow regulation, dentin production and its calcifying; it also may play some roles in dental pulp cells metabolism and differentiation.
