Chemical components in Hemsleya chensnsis (III).
- Author:
Jianyong DONG
1
;
Lei YUE
;
Weiwei SHAO
;
Jinzhong XU
Author Information
- Publication Type:Journal Article
- MeSH: Cucurbitaceae; chemistry; Magnetic Resonance Spectroscopy; Medicine, Chinese Traditional; Plant Roots; chemistry; Plants, Medicinal; chemistry; Saponins; chemistry; isolation & purification; Triterpenes; chemistry; isolation & purification
- From: China Journal of Chinese Materia Medica 2012;37(6):814-817
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents of Hemsleya chensnsis.
METHODVarious chromatographic techniques were used to separate and purify the constituents. The spectral data (MS, NMR) were obtained for structure elucidation.
RESULTEight known triterpenoid saponins were isolated from the root of H. chensnsis. Their structures were elucidated as dihydrocucurbitacin B (1), 25-O-acetyl-dihydrocucurbitacin F (2), cucurbitacin F (3), 3-O-(6'-ethyl ester) -beta-D-glucuropyranosyl oleanolic acid-28-O-alpha-L-arabinopyranoside (4), oleanolic acid-3-(6'-methyl ester) -beta-D-glucuropyranosyl (1-3) -alpha-L-arabinopyranoside (5), oleanolic acid-28-O-beta-D-glucopyranosyl-(1-6) -beta-D-glucopyranoside (6), 3-O-(6'-methyl ester) -beta-D-glucuropyranosyl oleanolic acid-28-O-beta-D-glucopyranosyl-(1-6) -beta-D-glucopyranoside (7), 3-O-(6'-methyl ester) -beta-D-glucuropyranosyl (1-2) -beta-D-glucopyranoside-oleanolic acid-28-O-beta-D-glucopyranoside (8).
CONCLUSIONAll compounds except for 2 were isolated from H. chensnsis for the first time.
