Application of network pharmacology and high through-put technology on active compounds screening from traditional Chinese medicine.

Author: Qingshan LIU ¹ ; Ziqian ZHANG ; Liang FANG ; Yifan JIANG ; Xiaoying YIN
Author Information

1. National Center of China for Minority Traditional Medical Research, Minzu University of China, Beijing 100081, China.
Publication Type:Journal Article
MeSH: Drug Delivery Systems; methods; Drug Evaluation, Preclinical; methods; Drugs, Chinese Herbal; administration & dosage; chemistry; isolation & purification; Humans; Medicine, Chinese Traditional; Pharmacology; methods; Technology, Pharmaceutical; methods
From: China Journal of Chinese Materia Medica 2012;37(2):134-137
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo solve the difficult in the active compounds screening from traditional Chinese medicines (TCM).
METHODAccording to preliminary lab results and related literature, systematic analysis of the high-throughput technology was made.
RESULTTechnologies of rapid preparation, high-throughput screening and biochip, together with the thought of drug target network, will contribute to TCM research on active ingredients screening, toxic components exclusion and molecular mechanisms. They are key technologies and ideas for modernization of TCM and research of TCM network pharmacology.
CONCLUSIONHigh throughput technology and network pharmacology-related technologies will provide new ideas and key methods for active compounds screening from TCM.