Chemical constituents from Corydalis yanhusuo.
- Author:
Ziming LU
1
;
Wuxing SUN
;
Xuhong DUAN
;
Zhiyun YANG
;
Yadong LIU
;
Pengfei TU
Author Information
- Publication Type:Journal Article
- MeSH: Adenosine; analysis; isolation & purification; Alkaloids; analysis; isolation & purification; Apomorphine; analogs & derivatives; analysis; isolation & purification; Aporphines; analysis; isolation & purification; Berberine; analysis; isolation & purification; Berberine Alkaloids; analysis; isolation & purification; Chromatography, Liquid; methods; Corydalis; chemistry; Plant Extracts; analysis; isolation & purification; Spectrometry, Mass, Electrospray Ionization; methods
- From: China Journal of Chinese Materia Medica 2012;37(2):235-237
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the chemical constituents of Corydalis yanhusuo.
METHODThe compounds were isolated and purified by column chromatography over macroporous absorption resin, silica gel, and Sephadex LH-20. Their structures were elucidated on the basis of physicochemical properties and spectral data.
RESULT22 compounds were isolated and identified as corydaline (1), tetrahydropalmatine (2), protopine (3), tetrahydrocorysamine (4), tetrahydrocoptisine (5) , tetrahydroberberine (6), tetrahydrocolumbamine (7), noroxyhydrastine (8), dehydrocorydaline (9), glaucine (10), columbamine (11), 8-oxocoptisine (12), 13-methyl-columbamine (13), coptisine (14), palmatine (15), herberine (16), oxoglaucine (17), 13-methyl-palmatrubine (18), dehydrocorybulbine (19), stepharanine (20), adenosine (21), and N5 -acetylornithine (22).
CONCLUSIONCompounds 13, 20, 21, and 22 were isolated from this plant for the first time.
