Study on chemical constituents of Artemisia sphaerocephala.
- Author:
Jie ZHANG
1
;
Linxi LI
;
Xiuhua LIU
;
Yong WANG
;
Dongbao ZHAO
Author Information
1. Key Laboratory of Natural Medicine and Immuno-Engineering, Henan University, Kaifeng 475004, China. jiezhang@henu.edu.cn
- Publication Type:Journal Article
- MeSH:
Artemisia;
chemistry;
Chromatography;
methods;
Flavones;
analysis;
isolation & purification;
Flavonoids;
analysis;
isolation & purification;
Glucosides;
analysis;
isolation & purification;
Plant Extracts;
analysis;
isolation & purification
- From:
China Journal of Chinese Materia Medica
2012;37(2):238-242
- CountryChina
- Language:Chinese
-
Abstract:
Further study on the chemical constituents of Artemisia sphaerocephala led to the isolation of fifteen compounds. These compounds were isolated and purified by repeated column chromatography on silica gel and Sephadex LH-20. Their structures were determined by physicochemical properties and spectral data analysis. These compounds were identified as 5-hydroxy-7,4'-dimethoxyflavanone (1), 5-hydroxy-7, 4'-dimethoxyflavone (2), 5-hydroxy-7, 4'-dimethoxyflavanonol (3), 5,3'-dihydroxy-7, 4'-dimethoxyflavanone (4), 5,7-dihydroxy-6,4'-dimethoxyflavone (5), isosakuranetin (6), hesperetin (7), navingenin (8), acacetin (9), chrysoeroil (10), 5,7-dihydroxy-4'-methoxyflavone-6,8-di-C- -glucopyranoside (11), didymin (12), acacetin-7-O-rutinoside (13), piceine (14), and capillarin (15). Compounds 1-3, 5, 7, 8, 10-15 were isolated from this plant for the first time.