Extended transsphenoidal operation for giant and invasive pituitary adenomas.
- Author:
Ren-zhi WANG
1
;
Jian YIN
;
Chang-bao SU
;
Zu-yuan REN
;
Yong YAO
;
Wei TAO
Author Information
- Publication Type:Journal Article
- MeSH: Adenoma; pathology; surgery; Adolescent; Adult; Aged; Female; Follow-Up Studies; Humans; Hypophysectomy; methods; Male; Microsurgery; Middle Aged; Neoplasm Invasiveness; Neuroendoscopy; Pituitary Neoplasms; pathology; surgery; Sphenoid Sinus; surgery; Treatment Outcome
- From: Chinese Journal of Surgery 2006;44(22):1548-1550
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the possibility of extended transsphenoidal approach for removing the giant and invasive pituitary adenomas.
METHODSThe clinical data of 64 cases with giant and invasive pituitary adenoma treated by extended transsphenoidal approach were studied retrospectively.
RESULTSAmong 64 patients, 51 had total resection and 13 had subtotal resection. 26 patients occurred transient diabetes insipidus, 5 patients with transient cerebrospinal rhinorrhoea and 1 patient occurred acute hypopituitarism postoperatively. There were no death or intracranial infection. After operation, 8 patients get radiotherapy, 6 patients receive medicine treatment. Postoperative follow-up period was 3 months to 6 years. No regrowth or recurrence was seen.
CONCLUSIONThe extended transsphenoidal approach has been proved to a safe and effective method to remove the giant and invasive pituitary adenomas. Patients who got subtotal resection need be close followed-up and receive radiotherapy or medicine treatment it necessary.
