Analyzing Chinese medicine syndromes of hematotoxicity reaction induced by highly active antiretroviral therapy.
- Author:
Zhi-Bin LIU
1
;
Xiu-Min CHEN
;
Yan-Tao JIN
Author Information
- Publication Type:Journal Article
- MeSH: Acquired Immunodeficiency Syndrome; drug therapy; Adult; Antiretroviral Therapy, Highly Active; adverse effects; CD4 Lymphocyte Count; Cross-Sectional Studies; Female; Humans; Male; Medicine, Chinese Traditional; Middle Aged; Quality of Life; Viral Load; Yang Deficiency; diagnosis; Yin Deficiency; diagnosis
- From: Chinese Journal of Integrated Traditional and Western Medicine 2012;32(6):751-753
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the main features of Chinese medicine (CM) syndromes and differences of hematotoxicity reaction induced by highly active antiretroviral therapy.
METHODSThe information of CM four diagnostic methods was collected by cross-sectional study. Their syndrome features were summed up and their differences were analyzed.
RESULTSOf the 216 patients, the main syndromes were qi-blood deficiency syndrome (142 cases, accounting for 65.7%) and Pi-Shen yang deficiency syndrome (74 cases, accounting for 34.3%). The score of qi-blood deficiency syndrome was obviously lower than that of Pi-Shen yang deficiency syndrome (P < 0.05). The count of CD4+ T cells was higher in qi-blood deficiency syndrome than in Pi-Shen yang deficiency syndrome. There was no statistical difference in the serum viral load between the two groups (P > 0.05). The quality of life was higher in qi-blood deficiency syndrome than in Pi-Shen yang deficiency syndrome, but with no statistical difference (P > 0.05).
CONCLUSIONSQi-blood deficiency syndrome and Pi-Shen yang deficiency syndrome were main syndromes of hematotoxicity reaction induced by HAART. The pathogenic condition of qi-blood deficiency syndrome patients was milder. There was no obvious difference in the quality of life, CD4+ T cells, and the viral loads between two syndromes.
