Clinical Observation on Effect of Amlodipine in Angina Pectoris.
10.4070/kcj.1991.21.6.1219
- Author:
Han Soo KIM
;
Ju Young YANG
;
Yang Soo JANG
;
Seung Jea TAHK
;
Won Heum SHIM
;
Seung Yun CHO
;
Sung Soon KIM
- Publication Type:Original Article
- MeSH:
Amlodipine*;
Angina Pectoris*;
Blood Pressure;
Dizziness;
Flushing;
Headache;
Heart Rate;
Hemodynamics;
Humans;
Male
- From:Korean Circulation Journal
1991;21(6):1219-1224
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We evaluated the clinical effects of amlodipine in 10 patients(7 male and 3 female) with angina pectoris in terms of the effect on the anginal pain, hemodynamic changes and side effects. The results obtained were as follows; 1) The clinical improvement was obsebed in 8(80.8%) of 10 and 9(88.9%) of 9 patients at 2 and 10 weeks after oral amlodipine. 2) The systolic and diastolic blood pressure was decreased significantly(136.0+/-16.5mmHg vs 117.0+/-10.6mmHg, p<0.01 and 85.0+/-9.7mmHg vs 75.0+/-5.3mmHg, p<0.01 respectively) but the heart rate was indepentent of amlodipine administration. 3) The adverse effects of amlodipine were as headache in 3, facial flushing in 3, palpitation, dizziness, urinary difficulty in 1 respectively and one of them discontinued amlodipine due to severe palpitation and facial flushing.
