Analysis on the frequency of urinary iodine in a population-based intervention study
10.3760/cma.j.issn.0254-6450.2012.05.010
- VernacularTitle:现场干预试验中人群尿碘频数的分析
- Author:
Yin-Yin SONG
1
;
Li-Hong MU
;
Ge LI
;
Yu-Lin WANG
;
Bang-Zhong XIAO
;
Xin-Shu LI
;
Yin LEI
Author Information
1. 重庆医科大学
- Keywords:
Urinary iodine level;
Urinary iodine frequency;
Community intervention;
Cohort
- From:
Chinese Journal of Epidemiology
2012;33(5):492-495
- CountryChina
- Language:Chinese
-
Abstract:
Objective Through a two-year follow up program,this study was to analyze the urinary iodine frequency of a cohort in the intervention trial,concerning different doses of salt iodization,so as to explore the selection of appropriate concentration of salt iodization.Methods A multistage cluster sampling method was used to select three townships in two countries for community intervention with different doses [ ( 15 ± 5 ) mg/kg,(25 ± 5 ) mg/kg,( 35 ± 5 ) mg/kg ] of salt iodization.Results After intervention,the median of urinary iodine was reduced among the population.The urinary iodine frequencies of (15 ± 5) mg/kg and (25 ± 5) mg/kg among groups of children were mainly concentrated in 100-200 μg/L and 200-300 μg/L paragraphs in A county.While the 300 μg/Lparagraph had an overall decline in B county,the 100 μtg/L and 200 μg/L paragraph ratio increased but the trend seemed to be slow.The 100-300 μg/L paragraph of the four treatment groups took a larger proportion and kept smooth in a more ideal state.However,the control group still maintained at above 250 μg/L level.Conclusion The iodine supplementation should be gradually implemented in Chongqing.The doses of salt iodization should be reduced from the current (35 ± 15)mg/kg to (25 ± 5) mg/kg in the economically developed areas.At the same time,we need to continuously follow the changes of the condition.
