Current status and influencing factors regarding quality of life among patients with Alzheimer's disease
10.3760/cma.j.issn.0254-6450.2012.06.014
- VernacularTitle:阿尔茨海默病患者生命质量现状及影响因素分析
- Author:
Min XING
1
;
Yong-Mei AI
;
Run-Lian HE
;
Jian-Wei GAO
;
Ping-Ping SONG
;
Xiao-Cheng WANG
;
Cai-Hong GAO
;
Hui-Min ZHANG
;
Hong-Mei YU
Author Information
1. 山西医科大学
- Keywords:
Alzheimer's disease;
Quality of life;
Influencing factors
- From:
Chinese Journal of Epidemiology
2012;33(6):606-609
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the current status and influencing factors regarding quality of life among patients with Alzheimer' s disease (AD).Methods Through stratified cluster sampling method,two hundred patients with AD and their caregivers were chosen and interviewed.AD patients were assessed by questionnaires,Montreal Cognitive Assessment,and Quality of LifeAlzheimer' s Disease (QOL-AD),in order to compare the reports from patients and caregivers on QOL-AD and to analyze related influencing factors.Descriptive analysis,paired t-test,analysis of variance (ANOVA),Pearson' s correlation and multiple linear regression were performed using the Statistical Package for Social Science (SPSS).Results The scores of reports from patients (28.78 ±4.30) were lower than that from the caregivers' (30.05 ± 6.05).The difference was statistically significant (t=2.122,P<0.05) and was positively correlated (r=0.312,P<0.001).Data from multivariate analysis showed that cognitive level (t=3.465,P=0.001),marriage relationship (t=3.062,P=0.003 ),having public activities (t =2.581,P=0.011 ),personal characters (t =2.254,P =0.026),restricted diet pattern (t=3.614,P<0.001),regularly drinking tea (t=2.652,P=0.009) and doing housework (t=3.180,P=0.002) were predictive factors.Conclusion Scores from the caregiver' s report on QOL-AD were higher than that from the patients'.Many factors influenced the quality of life on AD patients.Strategies on improving the quality of life among AD patients can be developed based on the findings of this study.