A clinical efficacy and safety study on coronary heart disease and angina treatment with Puerarin Injection

VernacularTitle:葛根素注射液治疗冠心病心绞痛的临床疗效和安全性研究
Author: Zhi-Kuan LUO ¹ ; Yong LIU ; Huan-Ming LI
Author Information

1. 天津市第四中心医院
Keywords: Puerarin Injection; Coronary heart disease; Angina; Effect
From: Chinese Journal of Epidemiology 2012;33(6):614-616
CountryChina
Language:Chinese
Abstract: Objective To observe the clinical efficacy and safety of Puerarin Injection treatment on angina pectoris.Methods 388 patients with angina pectoris,enrolled to Tianjin Fourth Central Hospital during January 2009 and February 2011 were selected and randomly divided into treatment or control groups with 194 patients of each.Based on the conventional therapy program,one group was given Puerarin Injection as treatment group while,the other was given with Danshen Injection as control group.Clinical efficacy,the attack rate of angina pectoris,oxygen consumption,iadices on electrocardiogram,haemorheology and other adverse reactions among the two groups were compared.Results The total efficacy of the treatment group (88.14％,171/194)was significantly higher than the control group (61.86％,120/194) and the difference was statistically significant (P＜0.05).During the treatment,no significant adverse events were noticed in both of the two groups of patients.Conclusion The Puerarin Injection treatment program on angina pectoris seemed effective and safe.