Solitary Pituitary Metastasis of Advanced Breast Cancer Treated with Anti-Human Epidermal Growth Factor Receptor 2 Drug.
- Author:
Jin Won JANG
1
;
Kyung Ae LEE
;
Won Sik JUNG
;
Ja Yeon LEE
;
Sunghoon CHOI
;
Yoon Chae LEE
Author Information
1. Institute of Clinical Medicine, Chonbuk National University Hospital, Jeonju, Korea. kaleey@jbnu.ac.kr
- Publication Type:Case Report
- Keywords:
Breast neoplasms;
Metastasis;
Pituitary gland;
Hyponatremia
- MeSH:
Aged;
Breast Neoplasms*;
Breast*;
Cranial Nerves;
Diabetes Insipidus;
Epidermal Growth Factor*;
Humans;
Hyponatremia;
Incidence;
Lung;
Neoplasm Metastasis*;
Pituitary Gland;
Pituitary Hormones, Anterior;
Receptor, Epidermal Growth Factor*;
Recurrence;
Visual Fields
- From:Soonchunhyang Medical Science
2015;21(2):110-112
- CountryRepublic of Korea
- Language:English
-
Abstract:
Metastasis to the pituitary gland from systemic cancer is a rare condition. The breast and lung are the most common sites of primary tumor metastasis. Most often, they occur in the setting of widespread metastatic disease, which most frequently occurs in elderly patients. However, an increase in the incidence of solitary pituitary metastasis of breast cancer as the first recurrence has been reported. Diabetes insipidus is the most frequent symptom at presentation, and visual field defects or cranial nerve deficits are common symptoms of pituitary metastasis. Unlikely these symptoms, deficiencies of anterior pituitary hormones may only become evident in critical situation because symptoms are of an insidious onset and sometimes nonspecific. We report here on a rare case of solitary pituitary metastasis from breast cancer presenting as hyponatremia without other symptoms.
