Related factors on patients with depression related to Alzheimer's disease based on the improved cumulative logistic regression

VernacularTitle:改进累积logistic回归对阿尔茨海默病伴抑郁患者影响因素研究
Author: Yan-Hong LUO ¹ ; Zhi-Xin GUO ; Jin-Yao WANG ; Yong-Mei AI ; Pei-Cui CHEN ; Hong-Mei YU
Author Information

1. 山西医科大学
Keywords: Alzheimer' s disease; Depression; Improved cumulative logistic regression
From: Chinese Journal of Epidemiology 2012;33(8):788-791
CountryChina
Language:Chinese
Abstract: Objective To explore the determinants of Alzheimer' s disease (AD) patients with depression.Methods The degree of depression on AD patients was assessed by the geriatric depression scale.Improved cumulative logistic regression (ICLR) was used to analyze the determinants of AD patients with depression.Results 196 AD patients were investigated.Among the 196 AD patients,there were 60(30.6％ ) males and 136(69.4％ ) females,at 58-89 years of age (72.3 ± 6.0).Physical activity,diabetes,MoCA,hearing,economic sources and alcohol were related to the degree of depression of AD patients (P＜0.10 ).The difference between “normal” and “mild depression” was smaller than difference between “mild depression” and “severe depression”.Conclusion AD patients with mild depression were the target population for prevention and they were influenced by several factors listed above.