Uterine Cervix Metastasis in Lung Adenocarcinoma with Anaplastic Lymphoma Kinase Rearrangement.
- Author:
Sooa CHOI
1
;
Chan Kwon PARK
;
Shin Young KIM
;
Hyoung Kyu YOON
;
Sang Mi RO
;
Yunju NAM
Author Information
1. Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. ckpaul@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Cervix;
Metastasis;
Anaplastic lymphoma kinase;
Lung neoplasms;
Adenocarcinoma of lung;
Crizotinib
- MeSH:
Adenocarcinoma*;
Adult;
Carcinoma, Non-Small-Cell Lung;
Cervix Uteri*;
Female;
Glycogen Storage Disease Type VI;
Humans;
Lung Neoplasms;
Lung*;
Lymphoma*;
Neoplasm Metastasis*;
Oncogenes;
Phosphotransferases*
- From:Soonchunhyang Medical Science
2015;21(2):142-145
- CountryRepublic of Korea
- Language:English
-
Abstract:
The importance of anaplastic lymphoma kinase (ALK) as an oncogene in non-small cell lung cancer (NSCLC) has emerged as a major concern due to a dramatic clinical effect of targeted therapy. As compared with the research for targeted therapy, the study about clinicopathological characteristics for ALK positive NSCLC hasn't been worked enough. Here, we describe a 35-year-old woman diagnosed with stage IVb NSCLC with ALK rearrangement. During evaluating her disease, a metastatic lesion to uterine cervix was found. Although lung cancer metastasis to female genital tract is rare, we also present case series that show a metastasis to the female genital tract in NSCLC with ALK rearrangement. These case series could suggest that ALK positive NSCLC has distinct metastatic pattern.
