A Case of Churg-Strauss Syndrome with Interstinal Perforation.
10.4046/trd.2009.66.5.374
- Author:
Jung Hoon PARK
1
;
Yun Seok JUNG
;
Yang Ki KIM
;
Young Mok LEE
;
Jung Hwa HWANG
;
Ki Up KIM
;
Dong Won KIM
;
Soo Taek UH
;
Jea Jun KIM
Author Information
1. Department of Internal Medicine, School of Medicine, Soonchunhyang University, Seoul, Korea. kukim@hosp.sch.ac.kr
- Publication Type:Case Report
- Keywords:
Churg-Strauss syndrome;
Asthma;
Intestinal perforation;
Eosinophilic infiltration
- MeSH:
Arteries;
Asthma;
Churg-Strauss Syndrome;
Eosinophilia;
Eosinophils;
Humans;
Intestinal Perforation;
Intestine, Small;
Mononeuropathies;
Polyneuropathies;
Purpura;
Sinusitis;
Vasculitis;
Veins
- From:Tuberculosis and Respiratory Diseases
2009;66(5):374-379
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Churg-Strauss syndrome (CSS) or allergic granulomatous angiitis is a rare syndrome that is characterized by hypereosinophilic systemic necrotizing vasculitis affecting small- to medium-sized arteries and veins. In general, it occurs in individuals with pre-existing allergic asthma. When CSS appears in patients, it has the following characteristics: eosinophilia of more than 10% in peripheral blood, paranasal sinusitis, pulmonary infiltrates, histological proof of vasculitis with extravascular eosinophils, and mononeuritis multiplex or polyneuropathy. Therapeutic trials dedicated to Churg-Strauss syndrome have been limited due to the rarity of this disorder and the difficulty in making a histological diagnosis. Proper treatment of patients with CSS is not widely known. In this case study, we report on our experience with an unusual patient case, characterized by purpura and a perforation of the small intestine after inadequate steroid therapy.
