Studies on chemical constituents of in herb Pyrola calliatha.
- Author:
Lei LIU
1
;
Yu-ping CHEN
;
Zhe WAN
;
An-liang LI
;
Ruo-yu LI
;
Peng-fei TU
Author Information
- Publication Type:Journal Article
- MeSH: Antifungal Agents; chemistry; isolation & purification; pharmacology; Cryptococcus neoformans; drug effects; Iridoids; chemistry; isolation & purification; pharmacology; Naphthoquinones; chemistry; isolation & purification; pharmacology; Plants, Medicinal; chemistry; Pyrola; chemistry; Triterpenes; chemistry; isolation & purification; pharmacology
- From: China Journal of Chinese Materia Medica 2007;32(17):1762-1765
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the chemical constituents of Pyrola calliatha.
METHODThe chemical constituents were isolated by various column chromatographic methods. The structures were identified by spectral data.
RESULTTen compounds were isolated and identified as chimaphilin (1), uvaol(2), ursolic acid (3), 2beta,3beta,23-trihydroxy-12-ene-28-ursolic acid (4), daucosterol (5), 2alpha,3beta,23,24-tetrahydroxy-12-ene-28-ursolic acid (6), emodin (7), gallic acid (8), monotropein (9), adenosine (10).
CONCLUSIONCompounds 2,4,6,7,10 were obtained from this genus for the first time, compounds 5, 9 were obtained from this species for the first time. Antifungal activity of compounds 1-4, 6-9 were evaluated. Compound 1 showed the strong activity.
