Studies on chemical constituents in seeds of Cicer arietinum.

Author: Yong-xia TAN ¹ ; Yu-hua SUN ; Ruo-yun CHEN
Author Information

1. Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine (Ministry of Education), Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China.
Publication Type:Journal Article
MeSH: Adenosine; chemistry; isolation & purification; Cerebrosides; chemistry; isolation & purification; Chromatography, Gel; Cicer; chemistry; Plants, Medicinal; chemistry; Seeds; chemistry; Triterpenes; chemistry; isolation & purification
From: China Journal of Chinese Materia Medica 2007;32(16):1650-1652
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo study the chemical constituents in seeds of Cicer arietinum, so that to find bioactive natural products.
METHODDried and sprouted seeds of C. arietinum were extracted with ethanol of various concentrations respectively, then isolated and purified by silica gel, macroreticular resin D 101, Sephadex LH -20 gel column chromatography, and structures of compounds were identified by spectral analysis.
RESULTNine compounds have been isolated and identified: 3-hydroxy-olean-12-ene (1), biochanin A-7-O-beta-D-glucoside (2), cerebroside (3), 1-ethyl-alpha-L-galactoside (4), uridine (5), adenosine (6), trytophan (7), biochanin A (8), fomononetin (9).
CONCLUSIONCompounds 1, 3, 4, 6, 7 were isolated from genus Cicer for the first time.