Study on drug properties of components in Euodiae Fructus based on rat stress gastric ulcer model with cold syndrome.
- Author:
Yong-Hai MENG
;
Qiu-Hong WANG
;
Bing-You YANG
;
Zhi-Xin YANG
;
Yan-Yan WANG
;
Zhi-Bin WANG
;
Hai-Xue KUANG
- Publication Type:Journal Article
- MeSH: Animals; Cold Temperature; adverse effects; Disease Models, Animal; Drugs, Chinese Herbal; pharmacology; therapeutic use; Female; Gastric Mucosa; drug effects; pathology; Male; Medicine, Chinese Traditional; Neurotransmitter Agents; blood; Rats; Rats, Wistar; Stomach Ulcer; blood; drug therapy; physiopathology; Stress, Physiological
- From: China Journal of Chinese Materia Medica 2014;39(3):498-502
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo clarify drug properties of components in Euodiae Fructus.
METHODThe rat cold syndrome model was induced by cold water stress method. The content of neurotransmitters sand hormones such as DA, 5-HT, NE, AChE and 17-OHCS in serum of model rats were taken as the indexes to evaluate drug properties of components in Euodiae Fructus.
RESULTEuodiae Fructus and its components could correct or relief the content of energy metabolism and substance metabolism-related neurotransmitters sand hormones in serum of model rats with water-stressed cold syndrome.
CONCLUSIONEuodiae Fructus and its components are proved to show hot property.