Orthogonal experiments to select spraying granulation technique for Baoshen granules.
- Author:
Cai-hong QU
1
;
Li YANG
;
Ji-wei HUANG
;
Qiong-liang ZHENG
Author Information
- Publication Type:Journal Article
- MeSH: Adhesives; Cyclodextrins; Drug Combinations; Drug Compounding; methods; Drugs, Chinese Herbal; administration & dosage; isolation & purification; Plants, Medicinal; chemistry; Powders; Temperature
- From: China Journal of Chinese Materia Medica 2005;30(20):1587-1588
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo raise the end-product and economical efficiency of spraying granulation, we demand screening preparation technique.
METHODAdopting newly spraying granulation technique, taking extracting technique, adhesive material, temperature of exit and entry,and the matching of accessories as inspecting factors, two levels of each factors, end-product as inspecting marker, we selected the best Baoshen granules preparation technique by orthogonal design.
RESULTAmong the 4 factors, adhesive material is most notable, next is temperature of exit and entry, the other two is of little importance.
CONCLUSIONThe optimum spraying granulation technique of Baoshen granules is A2B1C2D1.
