Study on electrochemical kinetics of matrine and sophoridine in a physiological medium.
- Author:
Zuo-ning GAO
1
;
Hui-qin YAO
;
Xiao-xia HAN
;
Jian-qiang YU
Author Information
- Publication Type:Journal Article
- MeSH: Alkaloids; chemistry; isolation & purification; Electrochemistry; methods; Electrodes; Kinetics; Oxidation-Reduction; Plants, Medicinal; chemistry; Quinolizines; chemistry; isolation & purification; Sophora; chemistry
- From: China Journal of Chinese Materia Medica 2005;30(23):1836-1839
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the kinetic processes of direct electrooxidation for both matrine and sophoridine in a physiological medium.
METHODTheir direct electrooxidative behaviors and the parameters of electrochemical kinetics were obtained by cyclic voltammetry (CV), bulk electrolysis with coulometry, chronocoulometry (CC), chronoamperometry (CA).
RESULT AND CONCLUSIONThe electrochemical experimental results show that the two totally irreversible oxidation peaks in the region of 0.3-1.2 V vs SCE for both MT and SR were observed, and the electrode reactions processes were diffusion-controlled. Their electron transfer number n and electron transfer coefficient alpha were obtained by CV and electrolysis with coulometry. The diffusion coefficient D and rate constant kf were also calculated by CC and CA.
