Correlation between tissue ultrastructure changes of small testis and sex hormone.
- Author:
Guo-An KE
1
;
Dao-Chou LONG
;
Sheng-Guo SHAN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Follicle Stimulating Hormone; metabolism; Gonadal Steroid Hormones; metabolism; Humans; Luteinizing Hormone; metabolism; Male; Statistics as Topic; Testis; anatomy & histology; metabolism; ultrastructure; Testosterone; metabolism
- From: National Journal of Andrology 2002;8(3):186-189
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVESTo investigate the tissue ultrastructure changes of small testis and sex hormone and their correlation.
METHODSThe patients were divided into small tests (n = 8) and control group(n = 12). FSH, LH, T were determined by radioimmunassay. Diameter and wall thickness of convoluted seminiferous tubule were investigated with light microscope and electro microscopy on small testis tissue morphology and ultrastructure.
RESULTSFSH, LH, T of small testis and control group were (21.05 +/- 9.15) IU/L vs (6.74 +/- 3.52) IU/L, (22.88 +/- 6.25) IU/L vs (6.60 +/- 1.48) IU/L and (0.30 +/- 0.04) nmol/L vs (17.55 +/- 9.25) nmol/L, respectively. Seminiferous tubule diameter and wall thickness were(37.33 +/- 6.80) microns vs (198.46 +/- 29.84) microns and (10.30 +/- 1.82) microns vs (2.95 +/- 0.20) microns. Small testis tissue ultrastructure changed significantly.
CONCLUSIONSPathologic changes of small testis tissue in many parts such as seminiferous tubule, germinal epithelium, Sertoli cell, Leydig cell, limiting membrance and blood vessel may relate with genetics and immunoreaction.
