The effect of acute urinary retention on serum prostate specific antigen concentration.
- Author:
Li-Xin HUA
1
;
Hong-Fei WU
;
Yuan-Geng SUI
;
Shuang-Guan CHENG
;
Zhen-Quan XU
Author Information
- Publication Type:Journal Article
- MeSH: Acute Disease; Aged; Aged, 80 and over; Humans; Male; Middle Aged; Prostate-Specific Antigen; blood; Prostatic Hyperplasia; blood; Urinary Retention; blood
- From:National Journal of Andrology 2002;8(2):134-135
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVESTo study the effect of acute urinary retention on the serum prostate-specific antigen (PSA) concentration.
METHODSBlood samples from 34 benign prostatic hyperplasia (BPH) patients with acute urinary retention were drawn immediately before suprapubic cystomy and 48 hours after relief of urinary retention. Serum PSA concentrations were measured with radioimmunoassay.
RESULTSThe mean serum PSA levels of BPH patients with acute urinary retention was (24.6 +/- 16.1) micrograms/L (range from 2.6 micrograms/L to 45.8 micrograms/L). Forty-eight hours after relief of urinary retention, the mean serum PSA levels declined to (9.4 +/- 6.3) micrograms/L (range from 1.7 micrograms/L to 16.6 micrograms/L). The difference was significant (P < 0.01).
CONCLUSIONSAcute urinary retention could dramatically increase the serum PSA value of patients with BPH. After relief of the urinary retention, the patients had a great than 50% decreased of PSA values.
