Treatment of external RF hyperthermia combining with alpha 1-adrenergic receptor blocker for patients with prostatodynia and chronic non-bacterial prostatitis.
- Author:
Jian WANG
1
;
Jian LI
;
Rong LU
;
Jun-Mei WANG
Author Information
- Publication Type:Clinical Trial
- MeSH: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; adverse effects; therapeutic use; Adult; Chronic Disease; Combined Modality Therapy; Humans; Hyperthermia, Induced; Male; Middle Aged; Pain; drug therapy; etiology; Pain Management; Prazosin; adverse effects; analogs & derivatives; therapeutic use; Prostatitis; complications; drug therapy; therapy
- From: National Journal of Andrology 2002;8(1):48-50
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVESTo evaluate a new effective treatment for prostatodynia (PD) and chronic non-bacterial prostatitis (CNP).
METHODSOne hundred and thirty-six patients suffered from PD or CNP were divided randomly into experiment group (n = 76), which were treated with external RF hyperthermia (ERFH) combining with alpha 1-adrenergic receptor blocker Terazosin for 12 weeks, and control group (n = 60), which were only treated with ERFH. Symptoms scores, urodynamic indexes and expressed prostate secretion were recorded pre- and post-treatments.
RESULTSMFR and AFR were significantly improved and symptoms scores significantly decreased in both groups (P < 0.05). The efficacy was better in experiment group than that in control group. The combination treatment also led to a significantly decrease in MUP and MUCP (P < 0.05). Additionally, the leucocytes in expressed prostate secretion were also reduced in experiment group (P < 0.05).
CONCLUSIONSTreatment of ERFH combining with alpha 1-adrenergic receptor blocker for patients with PD or CNP was effective and had little side-effect, while the future curative effect should be observed furtherly.
