Practicability study on a group of vigilant chemical compounds including chlorheridine diacetate.
- Author:
Xiao-Min FU
1
;
Ai-Hua JIN
;
Jian ZOU
;
Qian-Li LI
Author Information
- Publication Type:Journal Article
- MeSH: Acetates; pharmacology; therapeutic use; Anti-Bacterial Agents; pharmacology; therapeutic use; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; drug effects; Nitrophenols; pharmacology; therapeutic use; Sexually Transmitted Diseases; prevention & control; Spermatocidal Agents; pharmacology; therapeutic use; Spermatozoa; drug effects; Streptococcus; drug effects
- From: National Journal of Andrology 2002;8(5):329-331
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVESTo test in vitro the spermatozocidine drug which can also prevent sex transmitting diseases (STD) pathogens.
METHODSChlorheridine diacetate and other three chemical compounds were applied in vitro spermatozocidine and sperm inhibitting tests.
RESULTSThe lowest concentrations of chlorheridine diacetate and p-nitrophenol which can inhibit human sperm in 20 seconds were 1.25 mg/ml. The minimal inhibitory concentration and minimal bactericidal concentration of chlorheridine diacetate and p-nitrophenol on Streptococcus albus Stemberg were 0.125 to 0.50 mg/ml and 0.25 to 1.00 mg/ml.
CONCLUSIONSChlorheridine diacetate and p-uitrophenol have strong spermatozocidine and antibacteria effects.
