Survey of infection of Toxoplasma gondii in infertile couples in Suzhou countryside.
- Author:
Yong-Hua ZHOU
1
;
Yong-Juan LU
;
Rui-Bing WANG
;
La-Mei SONG
;
Fang SHI
;
Qing-Feng GAO
;
Ya-Fang LUO
;
Xing-Feng GU
;
Pei WANG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; China; epidemiology; Enzyme-Linked Immunosorbent Assay; Female; Humans; Infertility, Male; epidemiology; etiology; parasitology; Male; Toxoplasma; Toxoplasmosis; complications; epidemiology; parasitology
- From: National Journal of Andrology 2002;8(5):350-352
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVESTo determine the level of anti-Toxoplasma antibody in serum of infertile couples to explore the relationship between toxoplasma infection and infertility.
METHODSEnzyme-linked immunosorbent assay (ELISA) was applied to detect the anti-Toxoplasma antibody, antisperm antibody (AsAb) and anticardiolipin antibody (ACA) in serum of 178 couples with infertility and 190 couples who had normal pregnant history.
RESULTSThe positive result of Toxoplasma infection in the infertile couples was significantly higher than that in fertile couples which was 34.83% vs 12.11% (chi 2 = 26.72, P < 0.01) with the odds ratio 3.88. The positive result of serum AsAb in the Toxoplasma infected group was significantly higher than that in the no Toxoplasma infected group (32.50% vs 15.94%, chi 2 = 10.76, P < 0.01) with the odds ratio 2.54.
CONCLUSIONSToxoplasma infection was related to infertility. The Toxoplasma infection and was posibly related to the antisperm antibodies which can be involved in the pathogenisis of infertility.
