Study of the genes expression of SCD-2 and B-FABP in the mice brain of exercise-induced fatigue by genechip cDNA microarray.
- Author:
Liang TANG
1
;
Zhen-jun TIAN
;
Zheng-ying XIONG
;
Ying-qi ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Base Sequence; Brain; metabolism; Fatigue; genetics; metabolism; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; genetics; metabolism; Gene Expression; Male; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Nerve Tissue Proteins; genetics; metabolism; Oligonucleotide Array Sequence Analysis; Stearoyl-CoA Desaturase; genetics; metabolism
- From: Chinese Journal of Applied Physiology 2005;21(2):137-139
- CountryChina
- Language:Chinese
-
Abstract:
AIMBy genechip cDNA microarray, the genes expressions of Stearoyl-coenzyme A desaturase (Scd-2) and brain fatty acid-binding protein (B-FABP) were studied in the central nervous system (CNS) of the mice to discuss the mechanism of exercise-induced fatigue.
METHODSBuilding the model of fatigued animal and using the genechip cDNA microarray, the genes expressions were analyzed between the control group and fatigue group mice.
RESULTSThe genes expression of Scd-2 and B-FABP were obvious different in the brain of fatigued group mice than of control group.
CONCLUSIONExercise-induced nerve center fatigue is correlated with genes expressions of lipid metabolism.