Efficacy of highly active antiretroviral therapy for childhood acquired immunodeficiency syndrome.
- Author:
Jin-Li HAO
1
;
Bao-Jin WANG
;
Jean BAPTISTE
Author Information
- Publication Type:Journal Article
- MeSH: Acquired Immunodeficiency Syndrome; drug therapy; immunology; Adolescent; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Child; Child, Preschool; Female; Humans; Male; Retrospective Studies
- From: Chinese Journal of Contemporary Pediatrics 2010;12(11):874-876
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the efficacy of highly active antiretroviral therapy (HAART) for acquired immunodeficiency syndrome (AIDS) in children.
METHODSThe clinical data of 38 children (2-15 years old) with AIDS from a region of Rwanda and who had received HAART were retrospectively reviewed.
RESULTSAll of 13 children with anemia showed improved anemia symptoms after HAART. The hemoglobin contents returned to normal levels in 12 children with mild or moderate anemia. CD4 T lymphocytes increased by 24%-1 181% in 5 out of 6 cases with severe immunodeficiency after HAART. During the HAART, the weight gain averaged 2.3 kg yearly. The growth and development in 5 out of 8 children with delayed growth restored the levels of normal children of the same age after HAART.
CONCLUSIONSHAART can improve the health status in children with AIDS and is effective for childhood AIDS.
