Nasal carriage of community-acquired methicillin-resistant Staphylococcus aureus in healthy children from Chengdu.
- Author:
Juan FAN
1
;
Wei ZHOU
;
Min SHU
;
Jian-Jun DENG
;
Yu ZHU
;
Si-Yan DENG
;
Qin GUO
;
Chao-Min WAN
Author Information
- Publication Type:Journal Article
- MeSH: Bacterial Proteins; genetics; Carrier State; microbiology; Child; Child, Preschool; China; Community-Acquired Infections; microbiology; Female; Humans; Male; Methicillin-Resistant Staphylococcus aureus; genetics; isolation & purification; Microbial Sensitivity Tests; Nose; microbiology; Penicillin-Binding Proteins
- From: Chinese Journal of Contemporary Pediatrics 2011;13(1):16-19
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the prevalence of nasal carriage of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) in healthy children from Chengdu.
METHODSStrains of Staphylococcus aureus were isolated from nasal swabs of healthy children from five kindergartens in Chengdu from September, 2005 to December, 2005 and questionnaires were obtained. Antibiotic susceptibility test was performed with agar disk diffusion and Bauer-Kirby on Mueller-Hinton medium method to determine CA-MRSA. mecA and PVL genes were detected with PCR in all of the CA-MRSA isolates.
RESULTSA total of 801 children were enrolled. Overall 147 children (18.4%) were carried with Staphylococcus aureus and 9 (1.1%) were carried with CA-MRSA. All CA-MRSA isolates were positive for mecA gene, and 5 CA-MRSA isolates were positive for PVL gene. Of the 9 CA-MRSA isolates, 6 were multiresistant.
CONCLUSIONSCA-MRSA nasal colonization is present among Chengdu healthy children. The CA-MRSA isolates are multiresistant and parts of CA-MRSA isolates carry PVL gene. The nasal carriage of CA-MRSA in healthy children should be a concerned issue.
