Biofabrication with chitosan and its application progress.
- Author:
Fanping MENG
1
;
Aijing ZHANG
Author Information
1. College of Environmental Science and Engineering, Ocean University of China, Qingdao 266100, China. fanpingm@tom.cn
- Publication Type:Journal Article
- MeSH:
Biocompatible Materials;
chemistry;
Biomimetics;
Biosensing Techniques;
Catalysis;
Chitosan;
chemistry;
Micro-Electrical-Mechanical Systems;
methods;
Nanotechnology;
Nucleic Acid Hybridization
- From:
Chinese Journal of Biotechnology
2009;25(5):665-671
- CountryChina
- Language:Chinese
-
Abstract:
Chitosan is a polymer with good biocompatibility, unique pH-responsive solubility, convenient modification and easier film-formability. Chitosan could serve as an active mediator between biological components and microfabricated devices to prepare biological micro electro mechanical systems (BioMEMS) with high selectivity and sensitivity. Recently, there has been a growing interest in BioMEMS based on biofabrication of chitosan. We reviewed the mechanisms and processes of three biofabrication methods based on chitosan, including directed assembly, enzymatic assembly and self-assembly. Current applications and research progress in biological, medical and environmental fields are also discussed. Finally, future research directions are prospected.