Pancreatic Islet Cell Amyloidosis Manifesting as a Large Pancreas.
- Author:
Mehmet Ruhi ONUR
1
;
Mehmet YALNIZ
;
Ahmet Kursad POYRAZ
;
Ibrahim Hanifi OZERCAN
;
Yusuf OZKAN
Author Information
- Publication Type:Case Reports
- Keywords: Pancreas; Amyloidosis; Ultrasonography; Computed tomography; Magnetic resonance imaging
- MeSH: Adult; Amyloidosis/*diagnosis; Contrast Media/diagnostic use; Diagnosis, Differential; *Diagnostic Imaging; Female; Glucose Tolerance Test; Humans; Islets of Langerhans/*pathology; Pancreatic Diseases/*diagnosis
- From:Korean Journal of Radiology 2012;13(1):94-97
- CountryRepublic of Korea
- Language:English
- Abstract: A 39-year-old female patient presented to our hospital with epigastric pain lasting for two months. Laboratory results showed impaired glucose tolerance. Ultrasonography of the patient showed a hypoechoic, diffusely enlarged pancreas. CT revealed a large pancreas, with multiple calcifications. On MRI, a diffusely enlarged pancreas was seen hypointense on both T1- and T2-weighted images with heterogeneous enhancement after gadolinium administration. A biopsy of the pancreas revealed primary amyloidosis of islet cells. Decreased signal on T1-weighted images without inflammation findings on CT and MRI were clues for the diagnosis.
