Incidence of polynuclear zygotes and pregnancy rate after short coincubation of gametes in in vitro fertilization.
- Author:
Zhi-Peng XU
1
;
Hai-Xiang SUN
;
Ning-Yuan ZHANG
;
Lin-Jun CHEN
;
Bin WANG
;
Xia ZHAO
;
Jing ZHAO
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Embryo Implantation; Female; Fertilization in Vitro; Germ Cells; Humans; Male; Oocytes; Ovulation Induction; Pregnancy; Pregnancy Rate; Retrospective Studies; Zygote
- From: National Journal of Andrology 2012;18(9):807-810
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the relationship of the incidence of polynuclear zygotes with clinical pregnancy after short coincubation of gametes in in vitro fertilization (IVF).
METHODSWe retrospectively analyzed 3 862 cases of short gamete coincubation IVF, which were divided into six groups according to the percentage of polynuclear zygotes: 0,1-10%, 11-20%, 21-30%, 31-50%, 41-50%, and > or = 51%. We compared the rates of clinical pregnancy, implantation and abortion among the six groups.
RESULTSNo statistically significant differences were found in the patients'age, dose of gonadotropin, peak E2, number of follicles at the hCG trigger, and number of oocytes retrieved among the six groups. The 1-10% group showed higher rates of pregnancy and implantation, while the > or = 51% group exhibited lower rates of pregnancy and implantation but a higher rate of abortion than the other groups, none with significant differences (P > 0.05).
CONCLUSIONThe incidence of polynuclear zygotes after short coincubation of gametes in IVF cannot serve as a prognostic indicator of the outcome of clinical pregnancy.
