Relationship between maternal milk and serum thyroid hormones in patients with thyroid related diseases.
- Author:
Qian ZHANG
1
;
Xiao-lan LIAN
;
Xiao-feng CHAI
;
Yao BAI
;
Wei-xin DAI
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Female; Humans; Milk, Human; chemistry; Thyroid Diseases; blood; Thyroid Hormones; blood; chemistry; Thyrotropin; blood; chemistry; Triiodothyronine; blood; chemistry
- From: Acta Academiae Medicinae Sinicae 2013;35(4):427-431
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the relationship between maternal milk and serum thyroid hormones in patients with thyroid-related diseases.
METHODSSerum and breast milk samples were collected from 56 breastfeeding mothers. Milk and serum free triiodothyronine (FT3), free thyroxine (FT4), triiodothyronine(T3), thyroxine (T4), and thyrotrophin (TSH) were determined, and T3/T4 was calculated. Using the serum thyroid hormones as the independent variables and milk thyroid hormones as the dependent variables, we performed linear regression analysis.
RESULTSThe milk FT3, FT4, T3, T4, TSH, and T3/T4 were (2.30 ± 0.82) pg/ml ,(0.45 ± 0.26) ng/dl, (0.35 ± 0.20) ng/ml, (2.96 ± 1.55) Μg/dl, (0.12 ± 0.08) ΜU/ml, and 0.12 ± 0.04, respectively. Milk FT3 (r = 0.778, P = 0.000), T3 (r = 0.603, P = 0.000), T4 (r = 0.485, P = 0.004), and TSH (r = 0.605, P = 0.000) concentrations were positively correlated with those in serum.
CONCLUSIONThyroid hormones are present in human milk and are positively correlated with those in serum.
