Research advance in antitumor activities of artemisinin and its derivatives.
10.3881/j.issn.1000-503X.2013.04.021
- Author:
Hua YANG
1
;
Xian-jie TAN
Author Information
1. Department of Obstetrics and Gynecology, PUMC Hospital, Beijing, China.
- Publication Type:Journal Article
- MeSH:
Antineoplastic Agents;
pharmacology;
therapeutic use;
Apoptosis;
drug effects;
Artemisinins;
pharmacology;
therapeutic use;
Cell Cycle;
drug effects;
Humans;
Neoplasms;
drug therapy;
Neovascularization, Pathologic;
drug therapy
- From:
Acta Academiae Medicinae Sinicae
2013;35(4):466-471
- CountryChina
- Language:Chinese
-
Abstract:
Artemisinin and its derivatives are highly effective in fighting against malaria. Notably, these drugs have shown potent anti-timor activities by arresting cellular growth, enhancing apoptosis, inhibiting angiogenesis, and regulating the expression of tumor-associated genes, although the underlying mechanisms remain unclear.
