Biological changes after axonal stretch and their mechanisms.
10.3881/j.issn.1000-503X.2013.05.016
- Author:
Hong-ping HOU
1
,
2
;
Li-hai ZHANG
;
Li-cheng ZHANG
;
Xia LAN
;
Dao-hong LIU
;
Qi XIONG
;
Pei-fu TANG
Author Information
1. Department of Orthopaedics, Chinese PLA General Hospital, Beijing 100853, China
2. Medical College, Nankai University, Tianjin 300071, China.
- Publication Type:Journal Article
- MeSH:
Action Potentials;
Animals;
Axons;
metabolism;
pathology;
Cell Membrane;
pathology;
Cytoskeleton;
pathology;
Humans;
Stress, Mechanical
- From:
Acta Academiae Medicinae Sinicae
2013;35(5):571-575
- CountryChina
- Language:Chinese
-
Abstract:
Research on peripheral nervous injuries, especially the stretched injuries, is important to improve the clinical effectiveness and alleviate the patients's pain. In recent years, the biological changes and mechanics of stretched axons have been hot topics. This article reviews the recent advances in the morphological changes of axons as well as changes in cellular membrane, cytoskeleton, cellular metabolism, and action potential after axonal stretch.