Effects of bisphenol A on the female reproductive organs and their mechanisms.
10.3881/j.issn.1000-503X.2013.06.018
- Author:
Pei-pei YAN
1
;
Xiao-yan PAN
1
;
Xue-nan WANG
2
;
Zheng-chao WANG
3
;
Zhi-xin LI
1
;
Ying WAN
1
;
Zhi HE
1
;
Zhao-hua DOU
1
Author Information
1. Department of Histology and Embryology, Jilin Medical College, Jilin 132013, China.
2. Reproductive Medicine Center of the Affiliated Hospital of Jining Medical College, Jining, Shandong 272029, China.
3. Provincial Key Laboratory for Developmental Biology and Neurobiology, College of Life Science, Fujian Normal University, Fuzhou 350007, China.
- Publication Type:Journal Article
- MeSH:
Benzhydryl Compounds;
toxicity;
Endocrine Disruptors;
toxicity;
Estrogens, Non-Steroidal;
toxicity;
Female;
Humans;
Ovary;
drug effects;
Phenols;
toxicity;
Uterus;
drug effects;
Vagina;
drug effects
- From:
Acta Academiae Medicinae Sinicae
2013;35(6):683-688
- CountryChina
- Language:Chinese
-
Abstract:
Bisphenol A (BPA) is a commonly used phenolic environmental estrogen. Long-term exposure of female mammalians to BPA can lead to endocrine disorders, followed by the morphological and functional changes in ovary, uterus, vagina, and oviducts. The interactions of BPA with various target molecules or tissues will cause different effects. To further elucidate the effects of BPA on female reproductive system, we review the changes in the structure and functions of female reproduction system after BPA exposure and their possible mechanisms.
