Treatment and prognostic analysis of 1638 patients with non-small cell lung cancer.
- Author:
Chang-Li WANG
1
;
Dong-Sheng YUE
;
Zhen-Fa ZHANG
;
Li-Qun GONG
;
Yan-Jun SU
;
Jian YOU
;
Zhen ZHANG
;
Feng GU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; pathology; surgery; Female; Humans; Lung Neoplasms; pathology; surgery; Lymph Node Excision; Male; Middle Aged; Neoplasm Staging; Prognosis; Retrospective Studies; Survival Rate
- From: Chinese Journal of Surgery 2011;49(7):618-622
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the prognosis and prognostic factors of non-small-cell lung carcinoma (NSCLC) according the new TNM stage system.
METHODSClinic data of 1638 inpatient cases admitted from January 2001 to January 2005 were retrospectively reviewed. There were 1083 male and 555 female patients in the study and the average age was 59.5 years. All the patients received surgical procedures.
RESULTSThe overall 1, 3, 5-year survival rate was 80.0%, 52.3%, 39.0%. The main prognostic factors were bronchial stump, operation type, T stage, N stage, the number of lymph nodes (LNs) in lymph nodes dissection (1 - 10, 11 - 20, and > 20), overall N stations (< 4 and ≥ 4) and postoperative radiotherapy (all P < 0.05). Cox regression suggested that T stage (P = 0.000), N stage (P = 0.000), operation type (P = 0.001) and LNs (P = 0.013) were independent factors affecting the prognosis.
CONCLUSIONSThe overall survival rate of NSCLC is poor. T stage, N stage, operation type and LNs are independent factors affecting the prognosis.
