Clinical Characteristics and Outcomes of Acute ST-Segment Elevation Myocardial Infarction in Younger Korean Adults.
10.4070/kcj.2015.45.4.275
- Author:
Seung Hun LEE
1
;
Ju Han KIM
;
Myung Ho JEONG
;
Hyukjin PARK
;
Yun Ah JEONG
;
Youngkeun AHN
;
Jong Hyun KIM
;
Shung Chull CHAE
;
Young Jo KIM
;
Seung Ho HUR
;
In Whan SEONG
;
Taek Jong HONG
;
Donghoon CHOI
;
Myeong Chan CHO
;
Chong Jin KIM
;
Ki Bae SEUNG
;
Wook Sung CHUNG
;
Yang Soo JANG
;
Jeong Gwan CHO
;
Jong Chun PARK
;
Seung Jung PARK
Author Information
1. The Heart Center of Chonnam National University Hospital, Gwangju, Korea. kim@zuhan.com
- Publication Type:Original Article
- Keywords:
Myocardial infarction;
Young adult;
Prognosis
- MeSH:
Adult*;
Aged;
Chest Pain;
Dyslipidemias;
Humans;
Korea;
Male;
Myocardial Infarction*;
Prognosis;
Smoke;
Smoking;
Young Adult
- From:Korean Circulation Journal
2015;45(4):275-284
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND AND OBJECTIVES: This study aims to investigate the clinical features, angiographic findings, and outcomes of younger Korean ST-segment elevation myocardial infarction (STEMI) patients. SUBJECTS AND METHODS: We analyzed major adverse cardiac events (MACE) in the Korea Acute Myocardial Infarction Registry from November 2005 to October 2010. The registered patients were divided into two groups; young age group (<65 years) and old age group (> or =65 years). RESULTS: The young age group included 5281 patients (age, 53+/-7.8 years), and the old age group included 4896 patients (age, 74.3+/-6.5 years). Male gender, smoking, family history, dyslipidemia, and metabolic syndrome were more frequently observed in the young age group than in the old age group (89.5% vs. 59.3%, p<0.001; 77.3% vs. 47.2%, p<0.001; 11% vs. 4.6%, p<0.001; 11.2% vs. 7.7%, p<0.001; 67.6% vs. 62.9%, p<0.001). Most of the young Korean adults with STEMI complained of typical chest pain (89.8%), and they had a shorter symptom-to-door time (12+/-53.2 hours vs. 17.3+/-132 hours, p=0.010). The young age group showed a favorable prognosis, which was represented by the MACE, compared with the old age group at one month (1.8% vs. 2.8%, p=0.028), six months (6.8% vs. 8.2%, p<0.001), and twelve months (10.1% vs. 11.9%, p=0.025). However, there was no significant difference in the adjusted MACE rate at one month {hazard ratio (HR) 0.95, 95% confidence interval (CI) 0.60-1.51, p=0.828} and twelve months (HR 0.86, 95% CI 0.68-1.10, p=0.233). CONCLUSION: Younger Korean adults with STEMI have clinical outcomes similar to old aged patients, and therefore, they should be treated intensively like the elderly patients.
