Research traditional Chinese medicine properties by detecting rats' monoamine neurotransmitter after given two different traditional Chinese medicine.
- Author:
Junqing LI
1
;
Deqin ZHANG
;
Xiao ZHANG
;
Xi WANG
;
Sen ZENG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Biogenic Monoamines; metabolism; Brain; drug effects; metabolism; Chromatography, High Pressure Liquid; Curcuma; chemistry; Drugs, Chinese Herbal; pharmacology; Male; Neurotransmitter Agents; metabolism; Rats; Rats, Wistar
- From: China Journal of Chinese Materia Medica 2010;35(8):1022-1024
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo find out the essence of the traditional Chinese medicine properties from detecting the rats' monoamine neurotransmitter after given different traditional Chinese drug.
METHODThe property of rhizome curcumae and radix curcumae is opposite, they were given to rats respectively for one month. Next, HPLC-ECD method was used to detect the rats' monoamine neurotransmitter in different encephalic region.
RESULTRhizome curcumae can raise the rats' monoamine neurotransmitter, but radix curcumae inhibits the rats' monoamine neurotransmitter.
CONCLUSIONThere are correlations between the traditional Chinese medicine properties and monoamine neurotransmitter.
