Optimization of extraction process for compund kaliziran gel with orthogonal design.
- Author:
Yuan ZHAO
1
;
Jianguo XING
;
Xinchun WANG
;
Guipeng XUE
;
Xueliang DANG
Author Information
- Publication Type:Journal Article
- MeSH: Alcohols; chemistry; Chemical Fractionation; methods; Drugs, Chinese Herbal; analysis; isolation & purification; Plants, Medicinal; chemistry; Technology, Pharmaceutical; methods
- From: China Journal of Chinese Materia Medica 2010;35(9):1130-1133
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo optimize the extraction process of compund kaliziran gel.
METHODOrthogonal design was used to optimize the extracting process of eight herb medicines with the extract yield, the content of psoralen, isopsoralen and osthole as indexes, and to optimize the extracting process of Polygonum multflorumi and Seman sinapis albae with the extract yield and the content of 2,3,5,4'-tetrehydroxy-stilbene glucoside as indexes.
RESULTThe optimum extraction progress was as follows:eight herb medicines were extract 2 times for 1 hour with 8 times of 60% alcohol; P. multflorumi and S. sinapis albae were extract 2 times for 1 hour with 8 times of 40% alcohol.
CONCLUSIONThe optimum extraction processes are stable and feasible.
