Flavonoids and phenolic acid derivatives from flos farfarae.
- Author:
Di WU
1
;
Mian ZHANG
;
Chaofeng ZHANG
;
Zhengtao WANG
Author Information
- Publication Type:Journal Article
- MeSH: Flavonoids; analysis; isolation & purification; Flowers; chemistry; Hydroxybenzoates; analysis; isolation & purification; Plant Extracts; analysis; isolation & purification; Tussilago; chemistry
- From: China Journal of Chinese Materia Medica 2010;35(9):1142-1144
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the chemical constituents of the flower buds of Tussilago farfara.
METHODThe chemical constituents were isolated by silica gel and Sephadex LH-20 column chromatography, and structurally elucidated by spectral evidence together with physiochemical properties.
RESULTSeven flavonoids, quercetin (1), quercetin-3-O-beta-D-glucopyranoside (2), quercetin-4'-O-beta-D-glucopyranoside (3), hyperoside (4), rutin (5), kaempferol (6), kaempferol-3-O-alpha-L-rhamnopyranosyl-(1-6)-beta-D-glucopyranoside (7), together with eight phenolic acid derivatives, caffeic acid (8), methyl caffeate (9), ethyl caffeate (10), (E)-2,5-dihydroxycinnamic acid (11), 3,4-di-O-caffeoylquinic acid (12), 4,5-di-O-caffeoylquinic acid (13), methyl4,5-di-O-caffeoylquinate (14) and chlorogenic acid (15) were isolated from the flower buds of Tussilago farfara.
CONCLUSIONCompounds 7, 9-14 are isolated from this plant, also from this genus, for the first time.
