Optimization of combination modes of medical materials in extract of Huanglian Jiedu decoction by semi-bionic extraction.
- Author:
Jinming DOU
1
;
Xiumei SUN
;
Zhaowang ZHANG
;
Dingrong YU
;
Chao LI
Author Information
- Publication Type:Journal Article
- MeSH: Coptis; chemistry; Dosage Forms; Drugs, Chinese Herbal; analysis; isolation & purification; Gardenia; chemistry; Phellodendron; chemistry; Scutellaria baicalensis; chemistry
- From: China Journal of Chinese Materia Medica 2010;35(10):1256-1260
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo optimize the combination modes of medical materials in extract of Huanglian Jiedu decoction.
METHODDivided the medical materials of Huanglian Jiedu decotion into 15 groups and extracted by semi-bionic estraction (SBE), the contents of berberine, baicalin, geniposide, total alkaloid, total flavonoid, total integral calculus area of HPLC and extract of 1 000 were determined, standardized, weighted and evaluated, respectively.
RESULTThe maximum evaluated value Y for the extracting technique was AD + BC.
CONCLUSIONThe optimal combination mode of the perscription is that Rhizoma Coptidis and Fructus Gardeniae, Radix Scutellariae and Cortex Phellodendri Amurensis are decocted together respectively then the two decoctions are merged.
