Alkaloids in stems and leaves of Stephania cepharantha.
- Author:
Li HE
1
;
Yuanhu ZHANG
;
Lijia TANG
;
Shaohui SONG
;
Qianyun SUN
Author Information
- Publication Type:Journal Article
- MeSH: Alkaloids; analysis; isolation & purification; Plant Leaves; chemistry; Plant Stems; chemistry; Stephania; chemistry
- From: China Journal of Chinese Materia Medica 2010;35(10):1272-1275
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the alkaloids in the stems and leaves of Stephania cepharantha.
METHODThe dried stems and leaves of S. cepharantha were percolated with 95% ethanol and the solvent was removed by rotary evaporation to give a concentrate, and the concentrate was extracted by petroleum ether and chloroform. Column chromatograghy on MCI CHP 20P, silica gel, Rp-18, Sephadex LH-20 and polyamide were applied for the isolation and purification of the chloroform fraction. The structures were elucidated by their physicochemical properties and spectral data.
RESULTEleven alkaloids were obtained and identified as lysicamine (1), tetrahadropalmatine (2), palmatine (3), isocorydione (4), corydalmine (5), corypalmine (6), sinoracutine (7), sinoacutine (8), cepharamine (9), isocorydine (10) and corydine (11).
CONCLUSIONCompounds 2-7 were isolated from S. cepharantha for the first time, and compound 7 was isolated from the genus Stephania for the first time, compound 4 was isolated from the Menispermaceae family for the first time.
