Polymorphism of five short tandem repeat loci on chromosome X in Hebei Han population.
- Author:
Xue BAI
1
;
Bin CONG
;
Li-hong FU
;
Yu-xia YAO
;
Yan-mei ZHAO
;
Shu-jin LI
;
Yan-feng ZHEN
;
Yi WANG
;
Lei ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Alleles; Base Sequence; China; Chromosomes, Human, X; genetics; Female; Gene Frequency; Haplotypes; Humans; Male; Microsatellite Repeats; genetics; Molecular Sequence Data; Polymorphism, Genetic; genetics
- From: Chinese Journal of Medical Genetics 2006;23(5):574-577
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the polymorphism of DXS6801, DXS6809, DXS7423, DXS7424, DXS9902 five loci in Hebei Han population.
METHODSThe PCR products were detected by the polyacrylamide gel electrophresis and DNA sequencing analysis.
RESULTSAmong 114 irrelative males and 118 irrelative females from Hebei Han population, 31 alleles were found in the 5 loci. One hundred and one haplotypes of the male were detected and the haplotype diversity reached 0.9975.
CONCLUSIONThe five loci are relatively abundant in polymorphic information for identification and paternity test. And the obtained data of Hebei Han population can be applied to the X-short tandem repeat genetic data bank.
