Quantitative Morphology of the Frontal Lobe and the Caudate Nucleus in Boys with Attention Deficit/Hyperactivity Disorder.
- Author:
Seog Weon KONG
1
;
Jeong Seop LEE
;
In Kyoon LYOO
;
Kang EM HONG
Author Information
1. Department of Neuropsychiatry, Seoul National University Hospital, Korea.
- Publication Type:Original Article
- Keywords:
ADHD;
Frontal Lobe;
Caudate nucleus;
MRI;
Asymmetry
- MeSH:
Brain;
Caudate Nucleus*;
Frontal Lobe*;
Head;
Headache;
Humans;
Magnetic Resonance Imaging
- From:Journal of Korean Neuropsychiatric Association
1997;36(6):1162-1169
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: Because the caudate nucleus receives inputs from the dorsolateral prefrontal and orbitofrontal cortices, it is the area of the interest with ADHD patients in many researches. To identify the lack of normal asymmetry in the frontal lobe and caudate nucleus of the subjects with ADHD, one slice of brain MR images for each subjects were selected, and planimetric method was applied and analyzed. METHODS: The brain MR images of 14 ADHD boys who met the DSM-III-R diagnostic criteria and 16 headache control group were collected. Single best view far the head of the caudate nucleus, one axial slice was selected for analysis. MR images were redigitized with flatbed scanner and data were analyzed with Brainimage Pascal 2.3.3.1 software. Pixel counting and area measurements were done. Interrater reliabilities were 0.89 or greater. RESULTS: In both ADHD and control groups, right caudate area was slightly greater than left side, and this difference were more significant in control group. The results showed that the normal asymmetry of frontal lobe and the caudate nucleus was not observed for the ADHD group. CONCLUSION: The normal asymmetry of the frontal lobe and the caudate nucleus was not seen in boys with ADHD
