Advanced in studies on anxiolytic effects of natural flavonoids.

Author: Yue-Wei LV ¹ ; Jian-You GUO ² ; Yong LIU ¹ ; Jie LIU ¹ ; Min-Xuan WU ¹ ; Yuan-Song HE ¹ ; Jin-Li SHI ¹
Author Information

1. School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China.
2. Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China.
Publication Type:Journal Article
Keywords: anxiolytic effect; flavonoid; mechanism of action; neurotransmitter; structure-activity relationship
From: China Journal of Chinese Materia Medica 2016;41(1):38-44
CountryChina
Language:Chinese
Abstract: Anxiety is one of the most common diseases endangering human health. Its pathogenesis is complex, the studies on the mechanisms of anxiety disorder are concentrated on neurotransmitter, neuroendocrine, immunologic system. Flavonoids are a kind of compounds which possess a variety of physiological activity, used in plenty of diseases. In recent years, researches of natural flavonoids on anti-anxiety were increasing, but contents were incomplete. It was just involved several neurotransmitters in research area. This paper is based on different anxiolytic effect mechanisms and structure-activity relationships of natural flavonoids, summarizing the researches of domestic and foreign, which can serve as a reference for further studies on anxiolytic effects of natural flavonoids.