Evaluation of erectile function after urethral reconstruction: a prospective study.
- Author:
Hong XIE
1
;
Yue-Min XU
;
Xiao-Lin XU
;
Yin-Long SA
;
Deng-Long WU
;
Xin-Chi ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Erectile Dysfunction; etiology; physiopathology; Humans; Male; Middle Aged; Postoperative Complications; etiology; physiopathology; Prospective Studies; Quality of Life; Reconstructive Surgical Procedures; adverse effects; Self-Examination; Surveys and Questionnaires; Urethra; pathology; surgery; Urethral Stricture; pathology; surgery
- From: Asian Journal of Andrology 2009;11(2):209-214
- CountryChina
- Language:English
- Abstract: We conducted a prospective study of erectile dysfunction (ED) after urethral reconstructive surgery, using the 5-item International Index of Erectile Function (IIEF-5), the Sexual Life Quality Questionnaire (SLQQ) and the Quality of Life Questionnaire (QoLQ). Between January 2003 and July 2007, 125 male patients with urethral strictures underwent urethroplasty, and pre- and post-surgery erectile function was assessed using these three questionnaires. A formula to predict the probability of ED after urethroplasty was derived. At 3 months post-operatively, there was a significant decrease in IIEF-5 (16.57 +/- 7.98) and SLQQ scores (28.71 +/- 14.84) compared with pre-operative scores (P < 0.05). However, the IIEF-5 scores rebounded at 6 months post-operatively (17.22 +/- 8.41). Logistical regression analysis showed that the location of the urethral stricture, the recurrence of strictures and the choice of surgical technique were predictive of the post-operative occurrence of ED. This study identified the clinical risk factors for ED after urethroplasty. Posterior urethral stricture and end-to-end anastomosis were found to have a strong relationship with erectile function. The logistical model derived in this study may be applied to clinical decision algorithms for patients with urethral strictures.
