Effect of zhitiaokang capsule on serum insulin-like growth factor-2 in patients with hyperlipidemia.
- Author:
Mu-xiang YANG
1
;
Feng-zhe SU
;
Wen-tao YU
;
Yuanxiang TIAN
Author Information
- Publication Type:Clinical Trial
- MeSH: Adolescent; Adult; Aged; Capsules; Drugs, Chinese Herbal; therapeutic use; Female; Humans; Hyperlipidemias; blood; drug therapy; Hypolipidemic Agents; therapeutic use; Insulin-Like Growth Factor II; Male; Middle Aged; Phytotherapy; Proteins; metabolism
- From: Chinese Journal of Integrated Traditional and Western Medicine 2005;25(1):30-32
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the effect of Zhitiaokang capsule (ZTK) on serum insulin-like growth factor-2 (IGF-2) in patients with hyperlipidemia (HLP).
METHODSPatients with HLP were randomly divided into the treated group (n = 124) and the control group (n = 62), they were treated by ZTK and Zhibituo tablet respectively for 8 weeks as one therapeutic course. The changes of blood lipids and serum IGF-2 before and after treatment were observed.
RESULTSZTK could significantly reduce blood lipids and increase serum content of IGF-2.
CONCLUSIONZTK could improve the insulin resistant status and inhibit the development of hyperlipidemia in patients by means of raising serum content of IGF-2 and suppressing vascular endothelial cell apoptosis.
