Separation and purification technology of main active composition of Hongye Xingtong soft capsules with macroporous resin.
- Author:
Lin MA
1
;
Yong-Lin WANG
;
Ai-Min WANG
;
Yan-Yu LAN
;
Yong-Jun LI
;
Xun HE
;
Yong HUANG
Author Information
- Publication Type:Journal Article
- MeSH: Crataegus; chemistry; Drugs, Chinese Herbal; chemistry; isolation & purification; Polygonum; chemistry; Quercetin; analogs & derivatives; chemistry; isolation & purification; Resins, Synthetic; chemistry
- From: China Journal of Chinese Materia Medica 2008;33(5):505-508
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the technical conditions of the extraction and purification of the active composition from Polygonum orientale and Crataegus pinnatifida Bge. in Hongye Xingtong soft capsules with the macroporous resin.
METHODThe orientm, isorientm and hyperoside were used as index to screen the five kinds of resins. And the technical conditions of the enrichment and purification of D101 resin selected out of above were all-round studied.
RESULTThe D101 was fit for adsorbing orientm, isorientm and hyperoside. Under the optimal conditions, the transfer rate of orientm, isorientm and hyperoside was above 91%, and the total solid was cut down by more than 60%.
CONCLUSIONThe D101 is greatly effective for the enrichment and purification of the active composition of P. orientale and C. pinnatifida Bge.
